Hydrochlorothiazide (HCTZ)
6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide. Diuretic, thiazide diuretic.
This page describes what Hydrochlorothiazide (HCTZ) is and its known risks. It is not medical advice and not a guide to using it. Many of these substances are prescription-only or illegal to use without a prescription. Speak to a doctor.
- Class
- Diuretic
- Legal status
- Prescription only
- Half-life
- 6-15 hours
- Liver strain
- Low
- Kidney strain
- Moderate (with misuse)
- Converts to estrogen
- None
- Suppresses natural hormones
- Not typically
Medical uses
- Hypertension
- Edema
What it does in the body
Other
- Moderate fluid loss
Forms, half-life and detection
| Form | Half-life | Reported detection window |
|---|---|---|
| Oral | 6-15 hours | 1-2 days |
Side effects and health risks
Metabolic
- Electrolyte depletion (potassium, sodium, magnesium)
- Increased blood glucose (mild)
- Increased uric acid (gout risk)
Heart and blood vessels
- Blood pressure drops
- Dizziness
Kidneys
- Kidney strain with misuse
Blood tests worth monitoring
From its known properties, these are the markers doctors commonly check. Getting blood work before, during and after is how problems are caught early.
- Kidney strain: Moderate (with misuse): Creatinine, BUN, eGFR
Related compounds
Questions
What is the half-life of Hydrochlorothiazide (HCTZ)?
About 6-15 hours. Half-life is the time for the level in the blood to fall by half.
How long is Hydrochlorothiazide (HCTZ) detectable?
Testing windows of 1-2 days are reported, depending on the test and the person.
Is Hydrochlorothiazide (HCTZ) legal?
Prescription only. Laws differ by country and change; check the rules where you live.
What blood tests matter with Hydrochlorothiazide (HCTZ)?
Based on its properties, these markers are commonly monitored: Creatinine, BUN and eGFR. A doctor can order and interpret them.
What are the side effects of Hydrochlorothiazide (HCTZ)?
Metabolic: electrolyte depletion (potassium, sodium, magnesium), increased blood glucose (mild) and increased uric acid (gout risk). Heart and blood vessels: blood pressure drops and dizziness. Kidneys: kidney strain with misuse.
For information only, not medical advice. MyoStats is a tracking tool used at your own discretion. Speak to a doctor before changing your training, diet, medication or anything you take.