MK-677 (Ibutamoren)
2-amino-2-methyl-N-[(2R)-1-(2-methyl-1-oxo-2,7-dihydro-1H-spiro[indene-2,4'-piperidin]-1'-yl)-1-(3-(methylsulfonyl)phenyl)-... (growth hormone secretagogue). Growth Hormone Secretagogue, oral gh secretagogue / ghrelin mimetic.
This page describes what MK-677 (Ibutamoren) is and its known risks. It is not medical advice and not a guide to using it. Many of these substances are prescription-only or illegal to use without a prescription. Speak to a doctor.
- Class
- Growth Hormone Secretagogue
- Legal status
- Research chemical (not approved for human use)
- Half-life
- 24 hours
- Liver strain
- Low
- Kidney strain
- Low
- Converts to estrogen
- None
- Suppresses natural hormones
- Not typically
Medical uses
- None (clinical trials for muscle wasting and GH deficiency)
What it does in the body
Anabolic
- Increased GH and IGF-1 levels
- Increased lean mass (slow)
- Improved sleep quality
- Increased appetite (significant)
- Improved skin/hair quality
Forms, half-life and detection
| Form | Half-life | Reported detection window |
|---|---|---|
| Oral (liquid or capsules) | 24 hours | Unknown |
Side effects and health risks
Metabolic
- Increased blood glucose / insulin resistance
- Water retention
- Increased appetite (can be excessive)
Musculoskeletal
- Joint pain (mild)
- Numbness/tingling (carpal-tunnel-like)
Other
- Lethargy at high doses
Blood tests worth monitoring
From its known properties, these are the markers doctors commonly check. Getting blood work before, during and after is how problems are caught early.
- Affects blood sugar handling: Glucose (Fasting), HbA1c
Related compounds
- GHRP-2 (Growth Hormone Releasing Peptide-2)
- GHRP-6 (Growth Hormone Releasing Peptide-6)
- Hexarelin
- Sermorelin
- Tesamorelin (Egrifta)
Questions
What is the half-life of MK-677 (Ibutamoren)?
About 24 hours. Half-life is the time for the level in the blood to fall by half.
How long is MK-677 (Ibutamoren) detectable?
Testing windows of Unknown are reported, depending on the test and the person.
Is MK-677 (Ibutamoren) legal?
Research chemical (not approved for human use). Laws differ by country and change; check the rules where you live.
What blood tests matter with MK-677 (Ibutamoren)?
Based on its properties, these markers are commonly monitored: Glucose (Fasting) and HbA1c. A doctor can order and interpret them.
What are the side effects of MK-677 (Ibutamoren)?
Metabolic: increased blood glucose / insulin resistance, water retention and increased appetite (can be excessive). Musculoskeletal: joint pain (mild) and numbness/tingling (carpal-tunnel-like). Other: lethargy at high doses.
For information only, not medical advice. MyoStats is a tracking tool used at your own discretion. Speak to a doctor before changing your training, diet, medication or anything you take.