L-Citrulline
L-citrulline (or citrulline malate). Dietary Supplement, amino acid / nitric oxide precursor.
This page describes what L-Citrulline is and its known risks. It is not medical advice and not a guide to using it. Many of these substances are prescription-only or illegal to use without a prescription. Speak to a doctor.
- Class
- Dietary Supplement
- Legal status
- Over-the-counter (unrestricted)
- Half-life
- ~1 hour
- Liver strain
- None at typical doses
- Kidney strain
- None at typical doses
- Converts to estrogen
- None
- Suppresses natural hormones
- Not typically
Medical uses
- Urea cycle disorder management
What it does in the body
Cardiovascular
- Raises arginine and nitric oxide more reliably than arginine itself
- May improve blood flow and reps to fatigue (evidence mixed)
Forms, half-life and detection
| Form | Half-life | Reported detection window |
|---|---|---|
| Oral (powder) | ~1 hour | N/A (not a banned substance) |
Side effects and health risks
Gastrointestinal
- Stomach upset or loose stools in some people, mostly at high doses
Related compounds
Questions
What is the half-life of L-Citrulline?
About ~1 hour. Half-life is the time for the level in the blood to fall by half.
How long is L-Citrulline detectable?
Testing windows of N/A (not a banned substance) are reported, depending on the test and the person.
Is L-Citrulline legal?
Over-the-counter (unrestricted). Laws differ by country and change; check the rules where you live.
What blood tests matter with L-Citrulline?
Ask a doctor which tests suit you.
What are the side effects of L-Citrulline?
Gastrointestinal: stomach upset or loose stools in some people, mostly at high doses.
For information only, not medical advice. MyoStats is a tracking tool used at your own discretion. Speak to a doctor before changing your training, diet, medication or anything you take.